Description

15 α-Hydroxy-11-Oxoprogesterone is a synthetic steroid derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced steroid hormones and other bioactive molecules.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of steroid-based APIs.
• Biochemical Research: Investigated for its potential biological activity and role in enzymatic pathways.

Basic Information

Product Name	15 α-Hydroxy-11-Oxoprogesterone
CAS No.	855-05-0
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	15α-Hydroxy-11-oxoprogesterone; 15α-Hydroxypregn-4-ene-3,11,20-trione; 11-Oxo-15α-hydroxyprogesterone; 15α-Hydroxy-11-ketoprogesterone; 15α-Hydroxy-11-oxopregn-4-ene-3,20-dione; Pregn-4-ene-3,11,20-trione, 15α-hydroxy-; 15α-Hydroxy-11-oxo-progesterone
EINECS	Contact for details

Quality Control

Our 15 α-Hydroxy-11-Oxoprogesterone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.