Description

D-Glucaric Acid 1,4:6,3-Dilactone is a high-purity, versatile lactone derivative of glucaric acid, serving as a key intermediate and functional building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which provides reactive sites for creating biodegradable polymers, chelating agents, and specialty fine chemicals. This product is essential for research and development laboratories, pharmaceutical manufacturers, and companies in the personal care and detergent industries seeking sustainable and high-performance ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly those targeting metabolic pathways.
• Biodegradable Polymer Precursor: A critical monomer for producing environmentally friendly polyhydroxy acids and other bio-based polymers.
• Chelating Agent Synthesis: Serves as a starting material for manufacturing novel, biodegradable sequestering agents for detergents and water treatment formulations.
• Personal Care & Cosmetics: Incorporated into formulations for skin care products as a gentle exfoliant (polyhydroxy acid) and stabilizing agent.
• Food & Beverage Additive Precursor: Used in research for developing acidulants and preservatives with specific release profiles.
• Chemical Research & Development: Employed as a chiral building block and model compound in organic synthesis and catalysis studies.
• Cross-linking Agent: Utilized in the production of specialty resins and coatings that require controlled degradation properties.

Basic Information

Product Name	D-Glucaric Acid 1,4:6,3-Dilactone
CAS No.	826-91-5
Molecular Formula	C6H6O8
Molecular Weight	206.11 g/mol
Synonyms	Glucaro-1,4:6,3-dilactone; Saccharic Acid 1,4:6,3-Dilactone; D-Glucaro-1,4:6,3-dilactone; Glucaric Acid Dilactone; (3S,4S,5S,6R)-3,4,5,6-Tetrahydroxyoxepane-2,7-dione; L-Gulonic acid γ-lactone derivative
EINECS	212-577-8

Quality Control

Our D-Glucaric Acid 1,4:6,3-Dilactone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) that include HPLC assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after each use to prevent degradation due to moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.