Description

Dimethyl cis-1,2-Cyclopropanedicarboxylate is a high-purity, versatile diester building block featuring a strained cyclopropane ring, which is pivotal for introducing unique three-dimensional geometry and reactivity into target molecules. This compound is essential for advanced organic synthesis, serving as a key precursor for pharmaceuticals, agrochemicals, and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane motifs known for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of monomers for specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Utilized in [2+1] cycloadditions, ring-opening reactions, and other transformations to construct complex carbocyclic and heterocyclic systems.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing certain aroma chemicals with unique olfactory characteristics.

Basic Information

Product Name	Dimethyl cis-1,2-Cyclopropanedicarboxylate
CAS No.	826-34-6
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	cis-1,2-Cyclopropanedicarboxylic Acid Dimethyl Ester; Dimethyl Cyclopropane-1,2-dicarboxylate; Methyl cis-1,2-Cyclopropanedicarboxylate; cis-Cyclopropane-1,2-dicarboxylic Acid Dimethyl Ester; 1,2-Cyclopropanedicarboxylic Acid, Dimethyl Ester, cis-; NSC 66485; Dimethyl (1R,2S)-rel-1,2-Cyclopropanedicarboxylate
EINECS	Contact for details

Quality Control

Our Dimethyl cis-1,2-Cyclopropanedicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent isomeric composition. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
cis-Isomer Content (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.