Description

Estriol 16,17-Diacetate is a key pharmaceutical intermediate and reference standard, specifically the 16,17-diacetylated derivative of the natural estrogen estriol. This compound is valued for its high purity and stability, making it essential for research and development in steroid chemistry and hormone-related therapeutics. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories involved in the synthesis of steroid-based drugs, method development, and quality control.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and hormone replacement therapies.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical and research laboratories.
• Biochemical Research: Employed in studies investigating estrogen metabolism, receptor binding, and the biochemical pathways of steroid hormones.
• Academic & Industrial R&D: Serves as a starting material or reagent for novel compound synthesis in medicinal chemistry and life science research programs.

Basic Information

Product Name	Estriol 16,17-Diacetate
CAS No.	805-26-5
Molecular Formula	C23H30O5
Molecular Weight	386.48 g/mol
Synonyms	Estriol Diacetate; 16α,17β-Estriol 16,17-Diacetate; Estr-5(10)-ene-3,16α,17β-triol 16,17-diacetate; Oestra-1,3,5(10)-triene-3,16α,17β-triol 16,17-diacetate; 16,17-Diacetoxyestra-1,3,5(10)-trien-3-ol; 3-Hydroxyestra-1,3,5(10)-triene-16α,17β-diyl diacetate
EINECS	Contact for details

Quality Control

Our Estriol 16,17-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.