Description

Pteroyltriglutamic CAS NO 89-38-3 is a folate derivative and a key intermediate in the synthesis of more complex folic acid analogs. This compound is valued for its role in biochemical research and pharmaceutical development, particularly in the study of folate metabolism and enzyme inhibition. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic agents and nutritional supplements.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced folate-based drugs and targeted therapies.
• Biochemical Research: Used as a standard or reagent in studies investigating folate metabolism, enzyme kinetics, and one-carbon transfer pathways.
• Nutritional Science: Employed in the research and development of advanced nutritional supplements and fortified food products.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical and nutritional laboratories.
• Enzyme Inhibition Studies: Utilized to study the mechanism of action of dihydrofolate reductase (DHFR) and other folate-dependent enzymes.

Basic Information

Product Name	Pteroyltriglutamic
CAS No.	89-38-3
Molecular Formula	C26H31N9O9
Molecular Weight	589.58 g/mol
Synonyms	Pteroyltriglutamic Acid; Teropterin; PGA3; N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamyl-L-glutamyl-L-glutamic Acid; Folate Triglutamate; Prefolic A; NSC 529070; 89-38-3
EINECS	201-902-2

Quality Control

Our Pteroyltriglutamic is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.