Description

Octotiamine is a synthetic thiamine (vitamin B1) derivative, specifically an octanoic acid ester of thiamine. This chemical modification enhances its lipophilicity, which can improve absorption and bioavailability profiles compared to water-soluble thiamine salts. It serves as a key active pharmaceutical ingredient (API) and a premium nutritional supplement component for applications requiring enhanced metabolic support. Primary industrial demand comes from pharmaceutical manufacturers and producers of high-end nutraceutical and functional food formulations.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of prescription and over-the-counter medications targeting vitamin B1 deficiency syndromes, neurological support, and metabolic disorders.
• Nutraceutical & Dietary Supplements: A critical component in high-potency vitamin B-complex supplements, energy boosters, and specialized nutritional products due to its improved bioavailability.
• Functional Food & Beverage Fortification: Incorporated into health-focused foods and drinks designed to support energy metabolism and nervous system function.
• Veterinary Pharmaceuticals: Employed in vitamin premixes and therapeutic formulations for livestock, poultry, and companion animals to ensure proper growth and prevent deficiency-related conditions.
• Cosmeceutical Preparations: Utilized in advanced skincare products aimed at improving skin metabolism and providing antioxidant benefits.
• Research & Development: Serves as a standard or intermediate in biochemical research, metabolic studies, and the development of new therapeutic agents.

Basic Information

Product Name	Octotiamine
CAS No.	137-86-0
Molecular Formula	C19H26N4O3S
Molecular Weight	390.50 g/mol
Synonyms	Thiamine Octanoate; Octanoic acid, ester with thiamine; Thiamine monoocatanoate; Vitamin B1 octanoate; Allithiamine (related compound); TATD; O-DT; Lipophilic thiamine derivative; Thioctan
EINECS	205-304-5

Quality Control

Our Octotiamine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment. Production can be aligned with cGMP guidelines and relevant pharmacopoeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.