Description

Mecobalamin CAS NO 13422-55-4 is a biologically active form of vitamin B12, specifically a cobalamin derivative where a methyl group is bound to the central cobalt atom. This compound is critical for neurological health and cellular metabolism, serving as a vital coenzyme in the synthesis of methionine and the metabolism of fatty acids and amino acids. It is an essential raw material for the pharmaceutical, nutraceutical, and research industries, where high-purity standards are paramount for efficacy and safety in final formulations.

Application

• Pharmaceutical Formulations: Primary active ingredient in prescription and over-the-counter medications for treating vitamin B12 deficiency, peripheral neuropathy, and certain anemias.
• Nutraceuticals & Dietary Supplements: Key component in high-potency B-complex supplements, energy boosters, and specialized neurological support products.
• Clinical & Research Use: Used as a standard and reagent in biochemical research, clinical diagnostics, and cell culture media for studying methylation processes and nerve cell health.
• Veterinary Medicine: Incorporated into animal health products for livestock and companion animals to support metabolic function and treat deficiencies.
• Functional Food & Beverage Fortification: Employed in the fortification of foods and beverages aimed at supporting energy and cognitive health, though stability must be carefully managed.
• Cosmeceuticals: Included in topical skincare formulations for its purported benefits in skin rejuvenation and treating certain dermatological conditions.

Basic Information

Product Name	Mecobalamin
CAS No.	13422-55-4
Molecular Formula	C63H91CoN13O14P
Molecular Weight	1344.40 g/mol
Synonyms	Methylcobalamin; Co-methylcobalamin; Methyl B12; Mecobalamine; MeCbl; Vitamin B12a; Cobamamide (related); α-(5,6-Dimethylbenzimidazolyl)cobamide methyl; Methylcobalamin (USP); (SP-4-2)-[(Coα)-[α-(5,6-Dimethyl-1H-benzimidazol-1-yl)]-Coβ-methylcobamide]
EINECS	236-535-3

Quality Control

Our Mecobalamin is manufactured under strict quality management systems to meet the rigorous standards of the pharmaceutical and nutraceutical industries. Each batch is tested to ensure compliance with relevant pharmacopeial specifications such as USP, EP, and JP. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing key parameters including assay (HPLC), identification (IR/UV), specific optical rotation, related substances, and residual solvents. We are committed to full traceability and supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark red crystalline powder or crystals
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% ~ 102.0% (on anhydrous basis)
Specific Optical Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water (Karl Fischer)	≤ 12.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.