Description

Acefurtiamine is a synthetic derivative of thiamine (Vitamin B1) designed for enhanced stability and bioavailability. This compound is valued for its role as a potent precursor in the synthesis of active thiamine metabolites, crucial for cellular energy production and neurological function. It is primarily utilized by manufacturers in the pharmaceutical and nutraceutical industries for the development of high-performance dietary supplements and therapeutic formulations targeting metabolic and neurological support.

Application

• Active Pharmaceutical Ingredient (API) in neurological and metabolic health supplements.
• Key intermediate in the synthesis of advanced thiamine derivatives and prodrugs.
• Nutraceutical additive for premium vitamin B-complex and energy support formulations.
• Research chemical in preclinical studies investigating thiamine metabolism and neuroprotection.
• Component in specialized clinical nutrition products and medical foods.

Basic Information

Product Name	Acefurtiamine
CAS No.	10072-48-7
Molecular Formula	C15H23N4O3S2
Molecular Weight	371.50 g/mol
Synonyms	O,S-Diacetylthiamine; Acefultiamine; Acetylfurtiamine; Thiamine Diacetate; Vitamin B1 Diacetate; Allithiamine Derivative; Fursultiamine Analog; N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide acetate
EINECS	Contact for details

Quality Control

Our Acefurtiamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets exacting standards for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) documenting full compliance with specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.