Description

Pentaquine CAS NO 86-78-2 is a synthetic quinoline derivative with significant historical and research importance in medicinal chemistry. This compound serves as a critical intermediate and reference standard in the development and analysis of antimalarial agents. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and fine chemical manufacturers. Its well-defined structure makes it valuable for pharmacological studies and quality control processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced antimalarial compounds and related therapeutic agents.
• Research & Development: Used as a reference standard and active component in pharmacological and parasitological studies targeting malaria.
• Analytical Chemistry: Serves as a high-purity standard for method development and validation in HPLC, LC-MS, and other chromatographic techniques.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex quinoline-based molecular frameworks.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of aminoquinolines.
• Quality Control: Acts as a certified reference material (CRM) to ensure the purity and potency of commercial antimalarial drug products.

Basic Information

Product Name	Pentaquine
CAS No.	86-78-2
Molecular Formula	C₁₉H₂₇N₃O
Molecular Weight	313.44 g/mol
Synonyms	Pentaquine; SN-13,272; 6-Methoxy-8-(5-isopropylaminoamylamino)quinoline; 6-Methoxy-8-[5-(isopropylamino)pentylamino]quinoline; 8-[(5-Isopropylaminopentyl)amino]-6-methoxyquinoline; WR-2977; Pentaquine base
EINECS	Contact for details

Quality Control

Our Pentaquine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.