Description

Amodiaquine CAS NO 86-42-0 is a synthetic 4-aminoquinoline derivative with significant antimalarial activity. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of advanced antimalarial drugs. It is essential for pharmaceutical manufacturers and research institutions focused on developing and producing treatments for malaria, particularly in regions with chloroquine-resistant strains. Our supply ensures high purity and consistent quality for reliable formulation and research outcomes.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the core active component in antimalarial medication formulations.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of more complex antimalarial drug compounds.
• Biomedical Research: Used in in vitro and in vivo studies to investigate mechanisms of action against Plasmodium parasites.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Combination Therapy Development: A component in research for developing fixed-dose combination therapies to combat drug resistance.

Basic Information

Product Name	Amodiaquine
CAS No.	86-42-0
Molecular Formula	C20H22ClN3O
Molecular Weight	355.86 g/mol
Synonyms	4-[(7-Chloro-4-quinolyl)amino]-2-[(diethylamino)methyl]phenol; Amodiaquin; Amodiaquine Hydrochloride (salt form); Camoquin; Flavoquine; SN-10751; WR-142490; AQ
EINECS	201-673-8

Quality Control

Our Amodiaquine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets exacting standards suitable for pharmaceutical use. Certificates of Analysis (COA) are provided with each shipment, detailing all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.