Description

Quinacrine Dihydrochloride Dihydrate is a synthetic acridine derivative with significant biological activity. This compound is valued for its antimalarial and antiprotozoal properties, serving as a critical research tool and a reference standard in pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical manufacturers, and diagnostic laboratories for biochemical studies, drug discovery, and as a histological stain.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) in antimalarial and antiprotozoal drug studies.
• Biochemical Research: Employed as a fluorescent probe and inhibitor in cell biology to study processes like autophagy, prion disease mechanisms, and lysosomal function.
• Diagnostic Histology: Functions as a vital fluorescent stain for the detection of specific proteins and nucleic acids in tissue samples.
• Antimicrobial Agent Research: Investigated for its activity against various parasites, bacteria, and viruses in microbiological assays.
• Chemical Intermediate: Serves as a key synthetic precursor for the preparation of other acridine-based compounds.

Basic Information

Product Name	Quinacrine Dihydrochloride Dihydrate
CAS No.	83-89-6
Molecular Formula	C23H30ClN3O · 2HCl · 2H2O
Molecular Weight	508.90 g/mol
Synonyms	Mepacrine Dihydrochloride Dihydrate; Quinacrine HCl Dihydrate; Atebrin Dihydrochloride; Mepacrine Hydrochloride; 6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine Dihydrochloride Dihydrate; SN 390; Acriquine
EINECS	201-521-3

Quality Control

Our Quinacrine Dihydrochloride Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	6.0% - 8.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.