Description

Anisotropine Methylbromide is a quaternary ammonium anticholinergic agent, primarily recognized for its antispasmodic properties. This compound is valued for its targeted action on smooth muscle, making it a critical intermediate in the synthesis of specialized pharmaceutical formulations. It serves the needs of advanced pharmaceutical R&D and manufacturing sectors, particularly those developing treatments for gastrointestinal and genitourinary disorders. Its reliable performance and consistent quality are essential for ensuring the efficacy and safety of the final drug products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of antispasmodic and antisecretory medications.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production of APIs for treating gastrointestinal hypermotility and spasms.
• Research & Development: Employed in pharmacological studies to investigate anticholinergic mechanisms and develop new therapeutic agents.
• Formulation Development: Utilized in the development of solid dosage forms like tablets and capsules designed for controlled release.
• Reference Standard: Serves as a high-purity standard for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	Anisotropine Methylbromide
CAS No.	80-50-2
Molecular Formula	C18H28BrNO3
Molecular Weight	386.33 g/mol
Synonyms	Anisotropine Methyl Bromide; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2-phenylacetate methyl bromide; Octatropine Methylbromide; Valpin; Anisotropine Bromomethylate; Anisotropium Bromide; Methyl Anisotropinium Bromide
EINECS	201-289-7

Quality Control

Our Anisotropine Methylbromide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. We provide detailed Certificates of Analysis (COA) that document all critical quality attributes, and our processes are designed to support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.