Description

Propantheline Bromide is a quaternary ammonium anticholinergic agent primarily used as an antispasmodic. This compound is valued for its ability to inhibit muscarinic acetylcholine receptors, making it a critical active pharmaceutical ingredient (API) in specific therapeutic formulations. It is essential for manufacturers in the pharmaceutical industry developing medications for gastrointestinal disorders and other conditions requiring parasympathetic nervous system suppression.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in antispasmodic and antisecretory medications.
• Formulation component for drugs treating peptic ulcers, gastritis, and irritable bowel syndrome (IBS).
• Used in pharmaceutical research and development for neurological and gastrointestinal studies.
• Intermediate in the synthesis of more complex quaternary ammonium compounds.
• Reference standard in analytical laboratories for quality control and method validation.
• Potential applications in veterinary medicine for similar therapeutic effects.

Basic Information

Product Name	Propantheline Bromide
CAS No.	50-34-0
Molecular Formula	C23H30BrNO3
Molecular Weight	448.40 g/mol
Synonyms	Propanthelin Bromide; Pro-Banthine; (2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate; N-Methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-1-propanaminium bromide; Propantheline Bromide (USP); 9-Carboxy-xanthene propantheline bromide; 1-Methyl-2-(9H-xanthene-9-carbonyloxy)ethyl-diisopropyl-propyl-ammonium bromide
EINECS	200-034-5

Quality Control

Our Propantheline Bromide is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality is assured through a comprehensive battery of tests including identification, assay, and impurity profiling. Certificates of Analysis (COA) are provided with each batch, detailing compliance with relevant specifications. We adhere to GMP principles and our quality system is designed to ensure traceability and consistency for global regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.