Description

Scopolamine Butylbromide is a quaternary ammonium anticholinergic agent, also known as hyoscine butylbromide. This compound is valued for its potent antispasmodic properties, effectively relaxing smooth muscle in the gastrointestinal and genitourinary tracts. It is a critical active pharmaceutical ingredient (API) for manufacturers producing medications to treat abdominal cramps, spasms, and irritable bowel syndrome. Global pharmaceutical and fine chemical suppliers rely on high-purity Scopolamine Butylbromide CAS NO 149-64-4 for formulating injectable solutions, tablets, and other dosage forms.

Application

• Pharmaceutical API: Primary use as the active ingredient in antispasmodic and gastrointestinal motility inhibitor medications.
• Injectable Solutions: Formulation of parenteral drugs for rapid relief of renal or biliary colic and abdominal pain.
• Oral Solid Dosages: Manufacturing of tablets and capsules for the treatment of irritable bowel syndrome (IBS) and related gastrointestinal disorders.
• Pre-operative Medication: Used to reduce secretions and prevent reflex bradycardia before surgery.
• Diagnostic Aid: Administration in endoscopic procedures to reduce gastrointestinal motility for clearer visualization.
• Veterinary Medicine: Application in veterinary pharmaceuticals for treating colic and spasms in animals.

Basic Information

Product Name	Scopolamine Butylbromide
CAS No.	149-64-4
Molecular Formula	C21H30BrNO4
Molecular Weight	440.37 g/mol
Synonyms	Hyoscine Butylbromide; Butylscopolammonium Bromide; Buscopan®; Scopolamine Butobromide; (1R,2R,4S,5S,7s,9s)-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0²,⁴]nonane bromide; N-Butylscopolammonium Bromide; 6β,7β-Epoxy-8-butyl-3α-hydroxy-1αH,5αH-tropanium bromide (-)-tropate
EINECS	205-744-1

Quality Control

Our Scopolamine Butylbromide is manufactured and tested under strict quality management systems. We provide material that meets or exceeds Pharmaceutical Grade standards, with specifications aligned to major pharmacopoeias such as USP, EP, and BP. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance for GMP manufacturing. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.