Description

Tiemonium Iodide CAS NO 144-12-7 is a quaternary ammonium salt with anticholinergic and antispasmodic properties. This compound is a critical active pharmaceutical ingredient (API) and intermediate valued for its specific pharmacological activity. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of therapeutic agents targeting smooth muscle spasms in the gastrointestinal and urinary tracts.

Application

• Primary Active Pharmaceutical Ingredient (API) in antispasmodic and anticholinergic medications.
• Key intermediate in the synthesis of specialized pharmaceutical compounds.
• Research and development of new therapeutic agents for gastrointestinal disorders.
• Formulation of drugs for the treatment of urinary tract spasms and related conditions.
• Reference standard in analytical laboratories for quality control and method validation.
• Preclinical and clinical research studies in pharmacology.

Basic Information

Item	Detail
Product Name	Tiemonium Iodide
CAS No.	144-12-7
Molecular Formula	C20H26INO2S
Molecular Weight	495.40 g/mol
Synonyms	4-[3-Hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholinium iodide; Thiemonium iodide; Tiemonium Iodide; Tiemonium Iodide (USP); Tiemonium Iodide (EP); 4-Methyl-4-[3-oxo-3-(2-thienyl)-3-phenylpropyl]morpholinium iodide; Visceralgine; Polyspasmin
EINECS	205-618-5

Quality Control

Our Tiemonium Iodide is manufactured under strict quality management systems. We offer material compliant with major pharmacopoeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, residual solvents, and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.