Description

Benzilonium Bromide CAS NO 1050-48-2 is a quaternary ammonium salt compound primarily recognized for its anticholinergic and antispasmodic properties. This compound is valued for its ability to act as a smooth muscle relaxant, making it a critical active pharmaceutical ingredient (API) in therapeutic formulations. It is essential for manufacturers in the pharmaceutical industry developing medications for gastrointestinal disorders, such as peptic ulcers and irritable bowel syndrome, as well as for certain ophthalmic preparations.

Application

• Pharmaceutical API: Core active ingredient in antispasmodic and anticholinergic drug formulations.
• Gastrointestinal Therapeutics: Used in medications for treating peptic ulcers, gastritis, and irritable bowel syndrome (IBS).
• Ophthalmic Solutions: Employed in eye drops for pupillary dilation (mydriasis) and cycloplegia during eye examinations.
• Antisecretory Agents: Functions to reduce gastric acid secretion in relevant therapeutic applications.
• Pre-anaesthetic Medication: Used to reduce salivary and bronchial secretions before surgery.
• Intermediate for Synthesis: Serves as a chemical intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Benzilonium Bromide
CAS No.	1050-48-2
Molecular Formula	C21H26BrNO3
Molecular Weight	420.34 g/mol
Synonyms	Benzilonium bromide; 3-Hydroxy-1,1-dimethylpyrrolidinium bromide benzilate; 1,1-Dimethyl-3-hydroxy-pyrrolidinium bromide benzilate; Benziloyloxymethyl-1-methylpyrrolidinium bromide; N-Methyl-3-pyrrolidyl benzilate methobromide; P-252; Paragone; U-0457
EINECS	213-889-6

Quality Control

Our Benzilonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, impurity profiles, and residual solvents in compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.