Description

Amprotropine CAS NO 134-53-2 is a synthetic anticholinergic agent belonging to the tropane alkaloid class. This compound is valued for its specific pharmacological activity as a muscarinic acetylcholine receptor antagonist. It is primarily utilized in pharmaceutical research and development, serving as a key intermediate or reference standard in the synthesis and study of antispasmodic and anti-secretory drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced anticholinergic medications.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies targeting muscarinic receptors.
• Analytical Standard: Employed in quality control laboratories for method development and calibration in HPLC, GC, or LC-MS analyses.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of tropane derivatives.

Basic Information

Product Name	Amprotropine
CAS No.	134-53-2
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	Amprotropine; Tropine 3,5-Diaminobenzoate; 8-Azabicyclo[3.2.1]octan-3-yl 3,5-diaminobenzoate; 3α-Tropanyl 3,5-Diaminobenzoate; 3-Tropanyl m-3,5-Diaminobenzoate; Amprotropine Phosphate (salt form); Tropine Di(m-aminobenzoate)
EINECS	205-149-7

Quality Control

Our Amprotropine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.