Description

3-Pyridinecarbonitrile,5-(1S,5S)-3,6-Diazabicyclo[3.2.0]Hept-3-Yl-(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic diazabicyclo[3.2.0]heptane scaffold fused with a pyridinecarbonitrile moiety. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• API Synthesis: Integral building block for constructing the core scaffold of target APIs, especially those requiring chiral, nitrogen-rich bicyclic structures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	3-Pyridinecarbonitrile,5-(1S,5S)-3,6-Diazabicyclo[3.2.0]Hept-3-Yl-(9Ci)
CAS No.	799279-93-9
Molecular Formula	C12H12N4
Molecular Weight	212.25 g/mol
Synonyms	5-[(1S,5S)-3,6-Diazabicyclo[3.2.0]hept-3-yl]pyridine-3-carbonitrile; (1S,5S)-3-(5-Cyanopyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane; 3-(5-Cyano-3-pyridyl)-3,6-diazabicyclo[3.2.0]heptane (stereoisomer); Diazabicycloheptane-pyridinecarbonitrile derivative; CAS 799279-93-9; Pharmaceutical Intermediate 799279-93-9; Bicyclic amine nitrile intermediate.
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonitrile,5-(1S,5S)-3,6-Diazabicyclo[3.2.0]Hept-3-Yl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.