Description

1,3-Dioxolo[4,5-C]Pyridin-4(3Ah)-One,5-Aminotetrahydro-7-Hydroxy-2,2-Dimethyl-,(3As,7R,7As)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound with a complex fused-ring structure. This compound is valued as a critical pharmaceutical intermediate and advanced research chemical for the synthesis of novel active molecules. It is primarily sought by R&D laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its unique heterocyclic scaffold.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: The defined stereochemistry (3aS,7R,7aS) makes it a valuable chiral synthon for stereoselective chemical transformations.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic and medicinal chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and high-value performance materials.

Basic Information

Product Name	1,3-Dioxolo[4,5-C]Pyridin-4(3Ah)-One,5-Aminotetrahydro-7-Hydroxy-2,2-Dimethyl-,(3As,7R,7As)-(9Ci)
CAS No.	799277-34-2
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	(3aS,7R,7aS)-5-Amino-2,2-dimethyltetrahydro-7-hydroxy-3aH-[1,3]dioxolo[4,5-c]pyridin-4(3H)-one; 5-Aminotetrahydro-7-hydroxy-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyridin-4(3H)-one, (3aS,7R,7aS)-; Tetrahydro-7-hydroxy-2,2-dimethyl-5-amino-3aH-[1,3]dioxolo[4,5-c]pyridin-4(3H)-one; Fused Pyridone Derivative; Amino-hydroxy Dioxolopyridone; Chiral Dioxolopyridinone Intermediate; Stereoisomer 799277-34-2
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO compliant documentation for pharmaceutical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.