Description

5-Amino-2-(3-Methyl-Piperidin-1-Yl)-Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a benzamide core substituted with an amino group and a 3-methylpiperidine moiety. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors seeking reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new APIs with potential antipsychotic, antidepressant, or analgesic properties.
• Chemical Synthesis & Process Chemistry: Serves as a versatile building block for constructing more complex heterocyclic compounds in medicinal chemistry.
• Biochemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and receptor binding assays.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial drug substances.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	5-Amino-2-(3-Methyl-Piperidin-1-Yl)-Benzamide
CAS No.	799258-22-3
Molecular Formula	C13H19N3O
Molecular Weight	233.31 g/mol
Synonyms	5-Amino-2-(3-methyl-1-piperidinyl)benzamide; 2-(3-Methylpiperidin-1-yl)-5-aminobenzamide; Benzamide, 5-amino-2-(3-methyl-1-piperidinyl)-; 799258-22-3; 5-Amino-N-(3-methylpiperidin-1-yl)benzamide; 1-(5-Carbamoyl-2-aminophenyl)-3-methylpiperidine
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(3-Methyl-Piperidin-1-Yl)-Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.