Description

1-Cbz-5-Oxo-Piperidine-2-Carboxylic Acid Methyl Ester is a high-purity, protected piperidine derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of piperidine-based drug candidates, including protease inhibitors and neurological agents.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new therapeutic modalities.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability.
• Custom Synthesis & Contract Manufacturing: Employed in the production of bespoke fine chemicals and advanced intermediates under cGMP or research-grade conditions.
• Agrochemical Development: Utilized as a building block for creating novel compounds with potential pesticidal or herbicidal activity.

Basic Information

Product Name	1-Cbz-5-Oxo-Piperidine-2-Carboxylic Acid Methyl Ester
CAS No.	797801-61-7
Molecular Formula	C15H17NO5
Molecular Weight	291.30 g/mol
Synonyms	Methyl 1-[(benzyloxy)carbonyl]-5-oxopiperidine-2-carboxylate; 1-(Benzyloxycarbonyl)-5-oxopiperidine-2-carboxylic acid methyl ester; 1-Cbz-5-oxo-piperidine-2-carboxylic acid methyl ester; 1-Carbobenzyloxy-5-oxopiperidine-2-carboxylic acid methyl ester; Methyl 1-Cbz-5-oxopiperidine-2-carboxylate; 2-Piperidinecarboxylic acid, 5-oxo-1-[(phenylmethoxy)carbonyl]-, methyl ester; 797801-61-7
EINECS	Contact for details

Quality Control

Our 1-Cbz-5-Oxo-Piperidine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.