Description

Benzeneacetic Acid, α-(Hydroxymethyl)-4-Methyl-, Ethyl Ester, (Alphar)- (9Ci) is a specialized chiral ester derivative of benzeneacetic acid, valued for its role as a versatile synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a hydroxymethyl and an ethyl ester group on the alpha carbon, makes it a critical building block for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the specific stereoisomer can influence biological activity.
• Fine Chemical Manufacturing: Serves as a precursor in the synthesis of complex fragrances, flavors, and other specialty organic compounds.
• Academic & Industrial Research: Employed in methodological studies and process chemistry for developing new asymmetric synthesis routes.
• Material Science Precursor: Potential use in the synthesis of specialized monomers or ligands for advanced polymeric or catalytic systems.

Basic Information

Product Name	Benzeneacetic Acid, α-(Hydroxymethyl)-4-Methyl-, Ethyl Ester, (Alphar)- (9Ci)
CAS No.	797756-96-8
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	(αR)-α-(Hydroxymethyl)-4-methylbenzeneacetic acid ethyl ester; Ethyl (R)-2-(hydroxymethyl)-2-(4-methylphenyl)acetate; (R)-Ethyl 2-(hydroxymethyl)-2-(p-tolyl)acetate; (R)-Ethyl 2-(4-methylphenyl)-2-(hydroxymethyl)acetate; (R)-α-(Hydroxymethyl)-4-methylbenzeneacetic Acid Ethyl Ester; (R)-Ethyl 2-hydroxy-2-(4-methylphenyl)acetate (tautomeric form); Benzeneacetic acid, α-(hydroxymethyl)-4-methyl-, ethyl ester, (αR)-
EINECS	Contact for details

Quality Control

Our production of Benzeneacetic Acid, α-(Hydroxymethyl)-4-Methyl-, Ethyl Ester, (Alphar)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including HPLC, GC, and chiral analysis to confirm identity, potency, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.