Description

1H-Pyrrolo[2,3-B]Pyridine-2,5-Dicarboxylic Acid, 5-Methyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase-targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for the development of organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2,5-Dicarboxylic Acid, 5-Methyl Ester
CAS No.	797060-48-1
Molecular Formula	C11H8N2O4
Molecular Weight	232.19 g/mol
Synonyms	5-Methyl 1H-pyrrolo[2,3-b]pyridine-2,5-dicarboxylate; 1H-Pyrrolo[2,3-b]pyridine-2,5-dicarboxylic acid 5-methyl ester; Methyl 1H-pyrrolo[2,3-b]pyridine-2,5-dicarboxylate; 5-Methoxycarbonyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 797060-48-1; Pyrrolopyridine dicarboxylic acid methyl ester; Azaindole dicarboxylate derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2,5-Dicarboxylic Acid, 5-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.