Description

1-Cyclopropyl-1H-Imidazo[4,5-C]Pyridin-2(3H)-One Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in modern drug discovery. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the development of kinase inhibitors and other targeted small molecule drugs. It is essential for medicinal chemistry research and process development within the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Development: Core scaffold for research and production of potential kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in process development and cGMP manufacturing.
• Biochemical Research: Employed as a tool compound in biochemical assays and target validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex heterocyclic building blocks.

Basic Information

Product Name	1-Cyclopropyl-1H-Imidazo[4,5-C]Pyridin-2(3H)-One Hydrochloride
CAS No.	797032-01-0
Molecular Formula	C9H10N3O · HCl
Molecular Weight	209.66 g/mol (Free base: 173.20 g/mol)
Synonyms	1-Cyclopropyl-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one hydrochloride; 1-Cyclopropyl-2,3-dihydro-1H-imidazo[4,5-c]pyridin-2-one HCl; 1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2(3H)-one monohydrochloride; 1-Cyclopropylimidazo[4,5-c]pyridin-2(3H)-one hydrochloride; Imidazo[4,5-c]pyridin-2(3H)-one, 1-cyclopropyl-, hydrochloride; CAS 797032-01-0
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1H-Imidazo[4,5-C]Pyridin-2(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.