Description

6-(2,2,2-Trifluoro-Ethoxy)-Pyridin-3-Ol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoroethoxy substituent imparts desirable properties such as enhanced metabolic stability and lipophilicity, making it a sought-after intermediate for research and development. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the creation of novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for improved drug-like properties.
• Agrochemical Research: Building block for novel herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Material Science Precursor: Used in the synthesis of specialty chemicals, ligands for catalysis, and advanced polymers with specific electronic or surface properties.
• Life Science Reagent: Employed in biochemical and pharmacological research as a probe or modifier to study enzyme interactions and metabolic pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in bespoke synthesis projects.

Basic Information

Product Name	6-(2,2,2-Trifluoro-Ethoxy)-Pyridin-3-Ol
CAS No.	796120-81-5
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	3-Hydroxy-6-(2,2,2-trifluoroethoxy)pyridine; 6-(2,2,2-Trifluoroethoxy)-3-pyridinol; 6-(2,2,2-Trifluoroethoxy)pyridin-3-ol; 5-Hydroxy-2-(2,2,2-trifluoroethoxy)pyridine; 3-Pyridinol, 6-(2,2,2-trifluoroethoxy)-; 796120-81-5; Pyridine, 6-(2,2,2-trifluoroethoxy)-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 6-(2,2,2-Trifluoro-Ethoxy)-Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.