Description

5-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid is a high-value pyridine derivative and a versatile trifluoromethylated building block for advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a chloro-trifluoromethyl motif, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorine atoms into active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and metal-organic complexes used in catalysis.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid
CAS No.	796090-31-8
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	5-Chloro-4-(trifluoromethyl)picolinic acid; 2-Pyridinecarboxylic acid, 5-chloro-4-(trifluoromethyl)-; 5-Chloro-4-trifluoromethylpyridine-2-carboxylic acid; 5-Chloro-4-(trifluoromethyl)-2-picolinic acid; 796090-31-8; 5-Chloro-4-trifluoromethyl-2-pyridinecarboxylic acid; 4-Trifluoromethyl-5-chloropicolinic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory filings and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.