Description

3-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, combining a carboxylic acid group with chloro and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with tailored biological activity and material properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new small molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances bioavailability and stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials requiring specific fluorine-containing motifs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid
CAS No.	796090-27-2
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)picolinic acid; 2-Pyridinecarboxylic acid, 3-chloro-4-(trifluoromethyl)-; 3-Chloro-4-trifluoromethylpyridine-2-carboxylic acid; 3-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid; 796090-27-2; 3-Chloro-4-trifluoromethyl-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-(Trifluoromethyl)-2-Pyridinecarboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.