Description

6-Chloro-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its core value lies in the strategic combination of a carboxylic acid group, a chloro substituent, and a trifluoromethyl group on the pyridine ring, enabling precise molecular modifications. This compound is critically needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients, particularly as a precursor for complex amides and esters.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Used in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions and organocatalysts.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services and scale-up production under cGMP conditions.

Basic Information

Product Name	6-Chloro-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	796090-24-9
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-chloro-3-(trifluoromethyl)-; 6-Chloro-3-(trifluoromethyl)picolinic acid; 6-Chloro-3-trifluoromethylpyridine-2-carboxylic acid; 2-Carboxy-6-chloro-3-trifluoromethylpyridine; 6-Chloro-3-trifluoromethyl-2-pyridinecarboxylic acid; 796090-24-9; 6-Chloro-α,α,α-trifluoro-3-picolinic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.