Description

Benzeneacetic Acid, α-(Hydroxymethylene)-2-Methyl-, Ethyl Ester (9Ci) is a specialized organic ester compound with a reactive hydroxymethylene group, serving as a versatile building block in advanced chemical synthesis. Its molecular architecture makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for research and development chemists and process engineers in fine chemical manufacturing who require reliable, high-quality raw materials for producing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds requiring specific ester and hydroxymethylene functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and specialty polymers where its reactive group enables further chemical modifications.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for exploring new carbon-carbon bond formation reactions and constructing complex molecular frameworks.
• Flavor and Fragrance Industry: Potential use as an intermediate in the synthesis of specific ester-based aroma chemicals, subject to purity and regulatory compliance.

Basic Information

Item	Details
Product Name	Benzeneacetic Acid, α-(Hydroxymethylene)-2-Methyl-, Ethyl Ester (9Ci)
CAS No.	795274-97-4
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	Ethyl 2-(hydroxymethylene)-2-methylphenylacetate; Ethyl α-(hydroxymethylene)-2-methylbenzeneacetate; 2-Methylbenzeneacetic acid, α-(hydroxymethylene)-, ethyl ester; (Hydroxymethylene)(2-methylphenyl)acetic acid ethyl ester; Ethyl (hydroxymethylene)(o-tolyl)acetate; α-Formyl-2-methylphenylacetic acid ethyl ester; A potential Knoevenagel condensation product intermediate.
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetic Acid, α-(Hydroxymethylene)-2-Methyl-, Ethyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its reactive hydroxymethylene group, prolonged exposure to air and moisture should be minimized. Store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.