Description

5-Bromo-3-Methylpyridine-2-Carboxylic Acid Ethyl Ester is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development chemists requiring a functionalized heterocyclic scaffold to introduce complexity into target molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-3-Methylpyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	794592-13-5
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	Ethyl 5-Bromo-3-methylpicolinate; 5-Bromo-3-methyl-pyridine-2-carboxylic acid ethyl ester; 2-Pyridinecarboxylic acid, 5-bromo-3-methyl-, ethyl ester; 3-Methyl-5-bromopicolinic acid ethyl ester; Ethyl 5-bromo-3-methyl-2-pyridinecarboxylate; 794592-13-5; 5-Bromo-3-methyl-2-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Methylpyridine-2-Carboxylic Acid Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.