Description

Cyclopentanone, 2-Methyl-3-[(Trimethylsilyl)Ethynyl]- (9Ci) is a specialized organosilicon building block featuring a functionalized cyclopentanone core. This compound matters as a versatile synthon in advanced organic synthesis, where its unique combination of a ketone and a protected acetylene (ethynyl) group enables the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as medicinal chemistry and the synthesis of novel organic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Reagent: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira) and other metal-mediated transformations due to the trimethylsilyl-protected alkyne moiety.
• Chemical Research: Employed in academic and industrial laboratories for methodological development and the synthesis of complex natural product analogs or molecular scaffolds.
• Ligand and Catalyst Development: Provides a functional handle for constructing novel chelating ligands or organocatalysts.

Basic Information

Product Name	Cyclopentanone, 2-Methyl-3-[(Trimethylsilyl)Ethynyl]- (9Ci)
CAS No.	794523-86-7
Molecular Formula	C11H18OSi
Molecular Weight	194.35 g/mol
Synonyms	2-Methyl-3-[(trimethylsilyl)ethynyl]cyclopentanone; 3-[(Trimethylsilyl)ethynyl]-2-methylcyclopentanone; 2-Methyl-3-(trimethylsilylethynyl)cyclopentanone; 2-Methyl-3-(trimethylsilylethinyl)cyclopentanone; 2-Methyl-3-(trimethylsilyl-1-ethynyl)cyclopentanone; Cyclopentanone, 2-methyl-3-[(trimethylsilyl)ethynyl]-; TMS-protected alkyne cyclopentanone derivative
EINECS	Contact for details

Quality Control

Our Cyclopentanone, 2-Methyl-3-[(Trimethylsilyl)Ethynyl]- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by GC or HPLC), identity (by IR and/or NMR), and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Consider storing under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥95.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.