Description

Piperidine, 4-[(1E)-2-(2,6-Dimethylphenyl)Ethenyl]-3-Methyl-, (3R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical companies engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced crop protection agents and pesticides requiring specific stereochemistry for efficacy.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance ingredients, dyes, and other high-value specialty chemicals.
• Academic and Industrial Research: A valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Piperidine, 4-[(1E)-2-(2,6-Dimethylphenyl)Ethenyl]-3-Methyl-, (3R,4R)-Rel- (9Ci)
CAS No.	794472-45-0
Molecular Formula	C16H23N
Molecular Weight	229.36 g/mol
Synonyms	(3R,4R)-rel-4-[(1E)-2-(2,6-Dimethylphenyl)ethenyl]-3-methylpiperidine; 4-[(1E)-2-(2,6-Dimethylphenyl)ethenyl]-3-methylpiperidine, (3R,4R)-rel-; 794472-45-0; rel-(3R,4R)-4-[(1E)-2-(2,6-Dimethylphenyl)vinyl]-3-methylpiperidine; (E)-rel-(3R,4R)-4-[2-(2,6-Dimethylphenyl)vinyl]-3-methylpiperidine; 3-Methyl-4-[(1E)-2-(2,6-dimethylphenyl)ethenyl]piperidine, (3R,4R)-rel-
EINECS	Contact for details

Quality Control

Our Piperidine, 4-[(1E)-2-(2,6-Dimethylphenyl)Ethenyl]-3-Methyl-, (3R,4R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and MS, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.