Description

1H-Pyrazolo[3,4-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci) CAS NO 794451-98-2 is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrazolopyridine core with a trifluoromethyl substituent. This compound is valued for its unique heterocyclic structure, which is critical for modulating the biological activity and pharmacokinetic properties of target molecules in drug discovery. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting kinase inhibition.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged scaffold.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological profiling, ADMET studies, and in-vivo efficacy testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for clinical trial material.
• Chemical Biology: Utilized as a probe or tool compound for studying specific biological pathways and target validation.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with enhanced properties.

Basic Information

Product Name	1H-Pyrazolo[3,4-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci)
CAS No.	794451-98-2
Molecular Formula	C9H10F3N3
Molecular Weight	217.19 g/mol
Synonyms	4,5,6,7-Tetrahydro-1-methyl-3-(trifluoromethyl)-1H-pyrazolo[3,4-c]pyridine; 1-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine; 1H-Pyrazolo[3,4-c]pyridine, 4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-; 794451-98-2; 1-Methyl-3-trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine; Pyrazolo[3,4-c]pyridine, 4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.