Description

1H-Pyrazolo[4,3-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci) CAS NO 794451-94-8 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. Its core value lies in its unique molecular scaffold, which is integral to the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas such as oncology and central nervous system (CNS) disorders. This compound is essential for medicinal chemists and process development scientists in pharmaceutical R&D, fine chemical synthesis, and contract manufacturing organizations (CMOs) seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged heterocyclic structure.
• Process Chemistry Development: Employed in route scouting, scale-up studies, and the development of robust, GMP-compliant synthetic pathways for API manufacturing.
• Biochemical Probe Development: Acts as a core structure for creating chemical probes to study specific biological pathways and protein functions in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for the production of bespoke compounds for client-specific drug discovery programs.

Basic Information

Product Name	1H-Pyrazolo[4,3-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci)
CAS No.	794451-94-8
Molecular Formula	C9H10F3N3
Molecular Weight	217.19 g/mol
Synonyms	4,5,6,7-Tetrahydro-1-methyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine; 1-Methyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 1H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-; 794451-94-8; 1-Methyl-3-trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-1-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-C]Pyridine,4,5,6,7-Tetrahydro-1-Methyl-3-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material produced under quality guidelines suitable for advanced R&D and non-GMP pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. For long-term storage, consider refrigeration at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.