Description

(S)-1-(5-Bromo-3-Chloropyridin-2-Yl)Ethanamine CAS NO 793695-16-6 is a high-purity chiral amine building block featuring a halogenated pyridine core. This compound is a critical intermediate in the synthesis of advanced pharmaceutical active ingredients and agrochemicals, where its defined stereochemistry and reactive sites enable precise molecular construction. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, high-value target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and insecticides, leveraging its halogenated pyridine structure for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency and selectivity of synthetic transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a building block for novel organic electronic materials and metal-organic frameworks (MOFs) due to its functionalized heterocyclic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring high-purity chiral intermediates.

Basic Information

Product Name	(S)-1-(5-Bromo-3-Chloropyridin-2-Yl)Ethanamine
CAS No.	793695-16-6
Molecular Formula	C7H8BrClN2
Molecular Weight	235.51 g/mol
Synonyms	(S)-1-(5-Bromo-3-chloro-2-pyridinyl)ethanamine; (S)-1-(5-Bromo-3-chloropyridin-2-yl)ethan-1-amine; (S)-α-Methyl-5-bromo-3-chloro-2-pyridinemethanamine; (S)-5-Bromo-3-chloro-2-(1-aminoethyl)pyridine; (S)-2-(1-Aminoethyl)-5-bromo-3-chloropyridine; (S)-1-(5-Bromo-3-chloro-2-pyridyl)ethylamine; (S)-Enantiomer of 793695-16-6
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Bromo-3-Chloropyridin-2-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric excess (ee) and identity confirmation by NMR and MS. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.