Description

D-Proline, 4-Hydroxy-2-(Hydroxymethyl)-1-Methyl-5-Oxo-, Methyl Ester, (4S)- (9Ci) CAS NO 793682-88-9 is a high-purity, non-proteinogenic proline derivative characterized by its specific stereochemistry and functionalized side chain. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where precise stereocontrol is essential.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for protease inhibitors and other targeted drugs.
• Peptidomimetics Research: Used to synthesize modified peptide structures that mimic natural peptides but with enhanced stability or biological activity.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in catalytic and stoichiometric asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	D-Proline, 4-Hydroxy-2-(Hydroxymethyl)-1-Methyl-5-Oxo-, Methyl Ester, (4S)- (9Ci)
CAS No.	793682-88-9
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	(4S)-4-Hydroxy-2-(hydroxymethyl)-1-methyl-5-oxopyrrolidine-2-carboxylic acid methyl ester; Methyl (4S)-4-hydroxy-2-(hydroxymethyl)-1-methyl-5-oxo-D-prolinate; D-Proline derivative, 4-hydroxy-2-(hydroxymethyl)-1-methyl-5-oxo-, methyl ester; (4S)-4-Hydroxy-1-methyl-5-oxo-2-pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-, methyl ester; Proline, 4-hydroxy-2-(hydroxymethyl)-1-methyl-5-oxo-, methyl ester, (4S)- (9CI)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for purity, chiral purity (enantiomeric excess), and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.