Description

3-Amino-4-(4-Benzoyl-Piperazin-1-Yl)-Benzoic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique functional groups for targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a building block in the synthesis of compounds targeting protease enzymes.
• Kinase Inhibitor Development: Employed in the creation of potential kinase inhibitor candidates for oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	3-Amino-4-(4-Benzoyl-Piperazin-1-Yl)-Benzoic Acid Ethyl Ester
CAS No.	792946-70-4
Molecular Formula	C20H23N3O3
Molecular Weight	353.42 g/mol
Synonyms	Ethyl 3-Amino-4-(4-benzoylpiperazin-1-yl)benzoate; Benzoic acid, 3-amino-4-[4-(phenylcarbonyl)-1-piperazinyl]-, ethyl ester; 4-(4-Benzoylpiperazin-1-yl)-3-aminobenzoic acid ethyl ester; 3-Amino-4-(4-benzoyl-1-piperazinyl)benzoic acid ethyl ester; Ethyl 4-(4-benzoylpiperazin-1-yl)-3-aminobenzoate; 792946-70-4; AKOS025247317
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(4-Benzoyl-Piperazin-1-Yl)-Benzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.