Description

1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxamide is a high-value, multi-functional heterocyclic compound featuring a piperidine-carboxamide core linked to a trifluoromethyl-substituted pyridine moiety. This molecular architecture makes it a critical pharmaceutical intermediate and key building block in modern organic synthesis, particularly for the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine group.
• Chemical Biology & Medicinal Chemistry: Used in high-throughput screening and structure-activity relationship (SAR) studies to discover new drug candidates.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized fine chemicals and custom molecules.

Basic Information

Product Name	1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxamide
CAS No.	792940-04-6
Molecular Formula	C12H14F3N3O
Molecular Weight	273.25 g/mol
Synonyms	4-Carbamoyl-1-[5-(trifluoromethyl)-2-pyridyl]piperidine; 1-[5-(Trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxamide; Piperidine-4-carboxamide, 1-[5-(trifluoromethyl)-2-pyridinyl]-; 792940-04-6; 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxamide
EINECS	Contact for details

Quality Control

Our 1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.