Description

tert-Butyl 8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and carbamate-protected amine structure. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel, small-molecule drugs requiring precise stereochemistry and functional group manipulation.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex pharmaceutical compounds, especially those targeting neurological pathways.
• Peptidomimetic & Prodrug Development: Used in the design and synthesis of peptidomimetics and prodrugs due to its carbamate protecting group and rigid spirocyclic scaffold.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to introduce specific steric and electronic properties.
• Asymmetric Synthesis: Valuable chiral intermediate for constructing molecules with defined stereocenters, essential for enantioselective drug development.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying enzyme function and receptor interactions.

Basic Information

Product Name	tert-Butyl 8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Ylcarbamate
CAS No.	792913-82-7
Molecular Formula	C15H27NO4
Molecular Weight	285.38 g/mol
Synonyms	8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine, N-Boc derivative; tert-Butyl (8-methyl-1,4-dioxaspiro[4.5]decan-8-yl)carbamate; Boc-8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine; N-Boc-8-Methyl-1,4-dioxaspiro[4.5]decan-8-amine; 1,1-Dimethylethyl (8-methyl-1,4-dioxaspiro[4.5]decan-8-yl)carbamate; 8-(tert-Butoxycarbonylamino)-8-methyl-1,4-dioxaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Methyl-1,4-Dioxaspiro[4.5]Decan-8-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.