Description

Cyclohexaneacetic Acid, -α--Hydroxy-2-Oxo-, Ethyl Ester, (-α-S,1R)- (9Ci) is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its defined stereochemistry, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals with specific biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Employed as a building block in stereoselective reactions, including aldol condensations and nucleophilic additions, to introduce the α-hydroxy-β-ketoester moiety.
• Agrochemical Research: Used in the synthesis of novel, biologically active compounds for crop protection and pesticide development.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals where specific isomerism is required.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and catalysis focused on constructing quaternary stereocenters.

Basic Information

Product Name	Cyclohexaneacetic Acid, -α--Hydroxy-2-Oxo-, Ethyl Ester, (-α-S,1R)- (9Ci)
CAS No.	792909-04-7
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	(1R,2S)-Ethyl 2-Hydroxy-2-(2-oxocyclohexyl)acetate; (-)-(1R,2S)-Ethyl 2-Hydroxy-2-(2-oxocyclohexyl)acetate; Ethyl (1R,2S)-2-Hydroxy-2-(2-oxocyclohexyl)acetate; (1R,2S)-Ethyl 2-Hydroxy-2-(2-oxocyclohexyl)ethanoate; (αS,1R)-α-Hydroxy-2-oxocyclohexaneacetic Acid Ethyl Ester; Chiral Ethyl 2-Hydroxy-2-(2-oxocyclohexyl)acetate; Cyclohexanone-derived β-Ketoester
EINECS	Contact for details

Quality Control

Our Cyclohexaneacetic Acid, -α--Hydroxy-2-Oxo-, Ethyl Ester, (-α-S,1R)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.