Description

Spiro[2H-1-Benzopyran-2,4'-Piperidin]-4(3H)-One, 6-Chloro- is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is critical for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) and oncology fields. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the development of new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting cutting-edge organic synthesis and pharmacology research.
• Preclinical Development: Utilized in the production of compounds for toxicology, pharmacokinetics, and efficacy studies.

Basic Information

Product Name	Spiro[2H-1-Benzopyran-2,4'-Piperidin]-4(3H)-One, 6-Chloro-
CAS No.	792895-79-5
Molecular Formula	C14H14ClNO2
Molecular Weight	263.72 g/mol
Synonyms	6-Chlorospiro[2H-1-benzopyran-2,4'-piperidin]-4(3H)-one; 6-Chloro-4-oxospiro[chromene-2,4'-piperidine]; 6-Chloro-3H-spiro[1-benzopyran-2,4'-piperidine]-4-one; 6-Chloro-4-oxo-3H-spiro[chromene-2,4'-piperidine]; 6-Chloro-4-oxospiro[chromene-2,4'-piperidine]; 6-Chloro-spiro[chromene-2,4'-piperidin]-4-one; 6-Chloro-3H-spiro[benzopyran-2,4'-piperidin]-4-one
EINECS	Contact for details

Quality Control

Our Spiro[2H-1-Benzopyran-2,4'-Piperidin]-4(3H)-One, 6-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.