Description

(2S,3S)-2-Amino-2-Methyl-3-Hydroxybutyric Acid Methyl Ester CAS NO 791549-98-9 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at two chiral centers. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of enzyme inhibitors and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting proteases and other enzymes.
• Peptidomimetics Research: Used to construct peptide analogs with enhanced metabolic stability and bioavailability for drug discovery programs.
• Asymmetric Synthesis: Serves as a versatile starting material or auxiliary in stereoselective chemical reactions to introduce defined chiral complexity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate biological pathways and mechanisms.
• Agrochemical Development: Potential intermediate for creating chiral active ingredients in crop protection agents.
• Fine Chemical Synthesis: A valuable building block for custom synthesis and contract manufacturing of specialty chemicals.

Basic Information

Item	Details
Product Name	(2S,3S)-2-Amino-2-Methyl-3-Hydroxybutyric Acid Methyl Ester
CAS No.	791549-98-9
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	(2S,3S)-2-Amino-2-methyl-3-hydroxybutanoic acid methyl ester; Methyl (2S,3S)-2-amino-2-methyl-3-hydroxybutyrate; L-threonine derivative; (2S,3S)-AHMB Methyl Ester; 2-Amino-2-methyl-3-hydroxy-butyric acid methyl ester (2S,3S)-form; Amino hydroxy butyric acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of (2S,3S)-2-Amino-2-Methyl-3-Hydroxybutyric Acid Methyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as chiral purity, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (2S,3S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.