Description

L-Threo-Hex-4-Enuronic Acid, 4,5-Dideoxy-4-Methyl-2,3-o-(1-Methylethylidene)-, Methyl Ester, (4E)- (9Ci) is a sophisticated chiral building block and a key intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry and protected functional groups, which enable precise chemical transformations. It is primarily required by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), complex carbohydrates, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of complex drug molecules and potential therapeutic agents.
• Glycochemistry Research: Used as a building block for constructing deoxy sugar analogs, modified uronic acid derivatives, and complex oligosaccharides for biological studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Process Chemistry Development: Acts as a standardized intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic & Industrial R&D: Utilized in methodological development for stereoselective synthesis and exploring new catalytic reactions.
• Bioconjugate Chemistry: Potential use in the synthesis of labeled compounds or targeted drug delivery systems due to its modifiable functional groups.

Basic Information

Product Name	L-Threo-Hex-4-Enuronic Acid, 4,5-Dideoxy-4-Methyl-2,3-o-(1-Methylethylidene)-, Methyl Ester, (4E)- (9Ci)
CAS No.	791130-94-4
Molecular Formula	C11H16O5
Molecular Weight	228.24 g/mol
Synonyms	(4E)-4,5-Dideoxy-4-methyl-2,3-O-(1-methylethylidene)-L-threo-hex-4-enuronic acid methyl ester; Methyl (4E)-4,5-dideoxy-4-methyl-2,3-O-(1-methylethylidene)-L-threo-hex-4-enuronate; L-threo-Hex-4-enuronic acid, 4,5-dideoxy-4-methyl-2,3-O-(1-methylethylidene)-, methyl ester, (4E)-; 791130-94-4; Acetal-protected deoxy hexenuronic acid methyl ester; Chiral hexenuronic acid derivative
EINECS	Contact for details

Quality Control

Our L-Threo-Hex-4-Enuronic Acid derivative is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.