Description

5-Cbz-1-Oxa-5-Azaspiro[2.4]Heptane is a high-value, nitrogen- and oxygen-containing spirocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used in scaffold hopping and lead optimization to explore new chemical space and improve drug-like properties.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology: Useful for creating molecular probes and tool compounds to study biological pathways.
• Academic Research: Employed in methodological studies and the development of new synthetic routes involving spirocyclic systems.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	5-Cbz-1-Oxa-5-Azaspiro[2.4]Heptane
CAS No.	790704-73-3
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	5-[(Benzyloxy)carbonyl]-1-oxa-5-azaspiro[2.4]heptane; 1-Oxa-5-azaspiro[2.4]heptane-5-carboxylic acid benzyl ester; 5-Carbobenzyloxy-1-oxa-5-azaspiro[2.4]heptane; 5-Cbz-1-oxa-5-azaspiro[2.4]heptane; Benzyl 1-oxa-5-azaspiro[2.4]heptane-5-carboxylate; Spiro[cyclopropane-1,2'-[1,4]oxazinan]-5'-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our 5-Cbz-1-Oxa-5-Azaspiro[2.4]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), purity, and impurity profiles. Our quality commitment supports applications in GMP and non-GMP research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.