Description

6-Chloro-5-Iodo-3-Nitropyridin-2-Amine is a high-value, multi-functional halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by leveraging its halogenated pyridine core.
• Material Science: Serves as a building block for creating functionalized ligands, dyes, and photoactive materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution due to its reactive chlorine and iodine substituents.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	6-Chloro-5-Iodo-3-Nitropyridin-2-Amine
CAS No.	790692-90-9
Molecular Formula	C5H4ClIN3O2
Molecular Weight	315.46 g/mol
Synonyms	2-Amino-6-chloro-5-iodo-3-nitropyridine; 6-Chloro-5-iodo-3-nitro-2-pyridinamine; 5-Iodo-6-chloro-3-nitro-2-aminopyridine; 2-Pyridinamine, 6-chloro-5-iodo-3-nitro-; 790692-90-9; 6-Chloro-5-iodo-3-nitropyridin-2-ylamine; 3-Nitro-6-chloro-5-iodopyridin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodo-3-Nitropyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.