Description

6-Chloro-3-Nitro-5-Phenyl-Pyridin-2-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core functionalized with chloro, nitro, and phenyl substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a starting material for creating specialized ligands, catalysts, or organic electronic materials due to its electron-deficient aromatic system.
• Academic & Contract Research: Employed in university and CRO laboratories for method development, structure-activity relationship (SAR) studies, and combinatorial chemistry.
• Fine Chemical Synthesis: Utilized for the custom synthesis of complex, multi-functionalized pyridine derivatives for various specialty chemical applications.

Basic Information

Product Name	6-Chloro-3-Nitro-5-Phenyl-Pyridin-2-Ylamine
CAS No.	790692-86-3
Molecular Formula	C11H8ClN3O2
Molecular Weight	249.65 g/mol
Synonyms	2-Amino-6-chloro-3-nitro-5-phenylpyridine; 5-Phenyl-6-chloro-3-nitropyridin-2-amine; 6-Chloro-3-nitro-5-phenyl-2-pyridinamine; 2-Pyridinamine, 6-chloro-3-nitro-5-phenyl-; 790692-86-3; 6-Chloro-3-nitro-5-phenylpyridin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Nitro-5-Phenyl-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.