Description

3-Pyridinemethanol, α-(2,2-Dimethylpropyl)-α-(1H-1,2,4-Triazol-1-Ylmethyl)- is a specialized heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring both pyridine and triazole moieties, makes it a valuable building block for constructing complex molecules with targeted biological activity. This high-purity intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients. Its reliable synthesis and consistent quality are paramount for streamlining complex multi-step processes and accelerating time-to-market for new products.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Serves as a core scaffold for developing new generation fungicides, herbicides, and plant growth regulators, leveraging the bioactivity of the triazole ring system.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs, enabling the exploration of new chemical space.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or as a precursor for functional materials science applications.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services for clinical trial material and commercial-scale API production.

Basic Information

Product Name	3-Pyridinemethanol, α-(2,2-Dimethylpropyl)-α-(1H-1,2,4-Triazol-1-Ylmethyl)-
CAS No.	790691-19-9
Molecular Formula	C14H20N4O
Molecular Weight	260.34 g/mol
Synonyms	α-(2,2-Dimethylpropyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-3-pyridinemethanol; 1H-1,2,4-Triazole-1-methanol, α-(2,2-dimethylpropyl)-α-3-pyridinyl-; (RS)-α-(2,2-Dimethylpropyl)-α-(1,2,4-triazol-1-ylmethyl)pyridin-3-ylmethanol; (Rac)-α-Neopentyl-α-(1,2,4-triazol-1-ylmethyl)-3-pyridinemethanol; 3-Pyridinemethanol, α-(2,2-dimethylpropyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-; UNII-8V4A3N6OAZ; 8V4A3N6OAZ; (αRS)-α-(2,2-Dimethylpropyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-3-pyridinemethanol
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinemethanol, α-(2,2-Dimethylpropyl)-α-(1H-1,2,4-Triazol-1-Ylmethyl)- adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.