Description

1,3-Dioxolane-4,5-Dicarboxylicacid,2,2,4-Trimethyl-,4-Methylester,(4R,5S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its complex, functionalized dioxolane structure, which serves as a versatile precursor for constructing intricate molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its specific stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereocontrolled reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Institutional Research: A valuable compound for methodological studies in organic synthesis and stereochemistry at universities and R&D institutes.

Basic Information

Product Name	1,3-Dioxolane-4,5-Dicarboxylicacid,2,2,4-Trimethyl-,4-Methylester,(4R,5S)-Rel-(9Ci)
CAS No.	790662-12-3
Molecular Formula	C10H14O7
Molecular Weight	246.21 g/mol
Synonyms	(4R,5S)-rel-4,5-Bis(methoxycarbonyl)-2,2,4-trimethyl-1,3-dioxolane; 2,2,4-Trimethyl-1,3-dioxolane-4,5-dicarboxylic acid 4-methyl ester; (rel)-(4R,5S)-4,5-Dicarboxy-2,2,4-trimethyl-1,3-dioxolane 4-methyl ester; 1,3-Dioxolane-4,5-dicarboxylic acid, 2,2,4-trimethyl-, 4-methyl ester, (4R,5S)-rel-; Trimethyl dioxolane dicarboxylate methyl ester; Chiral dioxolane diester; Dioxolane carboxylate building block.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and stereochemical integrity using advanced analytical techniques. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and relevant impurities are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its ester and acetal functional groups, the material should be stored under inert conditions if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.