Description

Pyridine, 1,2,3,6-Tetrahydro-4-(Trifluoromethyl)- (9Ci) is a specialized heterocyclic compound featuring a partially saturated pyridine core substituted with a trifluoromethyl group. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for introducing fluorine-containing motifs which can dramatically alter the physicochemical properties of target molecules. It is primarily utilized by pharmaceutical and agrochemical research and development teams for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those requiring fluorinated scaffolds for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty chemicals, ligands for catalysis, and novel fluorinated polymers with unique surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic systems and in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Pyridine, 1,2,3,6-Tetrahydro-4-(Trifluoromethyl)- (9Ci)
CAS No.	790646-62-7
Molecular Formula	C7H8F3N
Molecular Weight	163.14 g/mol
Synonyms	4-(Trifluoromethyl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-(trifluoromethyl)pyridine; 4-Trifluoromethyl-1,2,3,6-tetrahydropyridine; 4-CF3-1,2,3,6-tetrahydropyridine; 4-(Trifluoromethyl)-3,6-dihydro-2H-pyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 1,2,3,6-Tetrahydro-4-(Trifluoromethyl)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.