Description

L-Alanine, n-Methylene-, 1,1-Dimethylethyl Ester (9Ci) CAS NO 788126-06-7 is a specialized, high-purity amino acid derivative featuring a tert-butyl ester protecting group. This compound is critical for advanced organic synthesis, particularly in the development of novel peptides and pharmaceutical intermediates where precise stereochemistry and functional group protection are required. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to create complex, bioactive molecules with high efficacy and specificity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected alanine derivative to control coupling reactions and prevent side reactions.
• Bioconjugation & Probe Development: Facilitates the creation of labeled peptides and proteins for diagnostic assays, imaging probes, and targeted drug delivery systems.
• Chemical Biology Research: Enables the study of protein-protein interactions, enzyme mechanisms, and the development of novel bioactive compounds in academic and industrial R&D.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring chiral purity and specific ester protection strategies.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel, chiral active ingredients for crop protection products.

Basic Information

Product Name	L-Alanine, n-Methylene-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	788126-06-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	tert-Butyl L-alaninate; (S)-2-Amino-propionic acid tert-butyl ester; L-Alanine tert-butyl ester; H-Ala-OtBu; Boc-Ala-OH tert-butyl ester precursor; (S)-tert-Butyl 2-aminopropanoate; Alanine, N-methyl-, 1,1-dimethylethyl ester, L- (9CI); tert-Butyl (S)-2-aminopropanoate
EINECS	Contact for details

Quality Control

Our production of L-Alanine, n-Methylene-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer and research-grade specifications. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.